Gm2a weight

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WebOct 17, 2024 · Summary: The GM2A protein reduces neural firing and induces a loss of neurite integrity. Alzheimer’s disease (AD) currently has no cure and is predicted to affect … Web康朗生物为您提供生物素蛋白连接酶抗体的参数及2024年最新报价，厂家专业的生物素蛋白连接酶抗体售后服务团队，是您值得 ...

GM2A Gene - GeneCards SAP3 Protein SAP3 Antibody

WebThe phenotype of previously described GM2A patients has been typified by onset in infancy, profound hypotonia and impaired volitional movement, intractable seizures, hyperacusis, and a macular cherry red spot. Our findings expand the phenotypic spectrum of GM2A mutation-positive gangliosidosis to include generalized chorea without macular ... WebThe GM2A gene provides instructions for making a protein called the ganglioside GM2 activator. This protein is necessary for the normal function of an enzyme called beta … oregon belts by size

GM2A gene: MedlinePlus Genetics

WebDisclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation … WebDisclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation … WebDec 8, 2024 · cd00258. Location:32 → 193. GM2-AP; GM2 activator protein (GM2-AP) is a non-enzymatic lysosomal protein that acts as cofactor in the sequential degradation of … how to unblock a user in roblox

Elevated ganglioside GM2 activator (GM2A) in human brain

Mutation in GM2A Leads to a Progressive Chorea-dementia …

WebMar 21, 2024 · GM2A (Ganglioside GM2 Activator) is a Protein Coding gene. ... tendons, ligaments, joints, and other connective tissue. The musculoskeletal system supports the weight of the body, maintains body … WebPredicted molecular weight. 19 kDa including tags. Amino acids. 33 to 193. Tags. His tag N-Terminus. Associated products. Related Products. Anti-GM2A antibody ... Defects in … how to unblock a website on eeroWebSep 21, 2024 · Elevated ganglioside GM2 activator (GM2A) associates with reductions in both NI and MEA activity, and cell-derived GM2A alone is sufficient to induce a loss of … how to unblock axis bank credit card online

"WebOur GM2A polyclonal and monoclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Relative expression to confirm specificity to GM2A. Find the GM2A antibody that fits your needs. Choose from 1 of 14 GM2A antibodies, which have been validated in experiments with 2 publications and 34 images featured in ... " - Gm2a weight

Gm2a weight

WebDisclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. ... There are no reviews for GM2A Recombinant Protein (H00002760-P01). WebAlthough GM2A as a diagnostic and prognostic marker in BC should be carefully veriﬁed further, this study has established the potential role of GM2A in BC progression. B reast cancer is a major common cancer in women world …

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The protein encoded by this gene is a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme β-hexosaminidase A. β-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. GM2A is a lipid transfer protein that stimulates the enzymatic processing of gangliosides, and also T … WebFeb 8, 2024 · Table 2. Stem cell frequencies in GSCs (1517, 3565, and 3691) transduced with shCONT or shGM2A. GM2 ganglioside catabolism is critical to maintain GSC stemness. GM2A is a sphingolipid protein that presents GM2 gangliosides to the lysosomal β-hexosaminidase enzymes (HEXA and HEXB) for catabolism in lysosomes ( 48, 52 ).

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WebUse a concentration of 1 - 2 µg/ml. Predicted molecular weight: 21 kDa. A 1 hour primary incubation is recommended for this product. Notes; WB ... Defects in GM2A are the cause of GM2-gangliosidosis type AB (GM2GAB) [MIM:272750]; also known as Tay-Sachs disease AB variant. GM2-gangliosidosis is an autosomal recessive lysosomal storage disease ... WebAug 25, 2024 · Establishing the Diagnosis. The diagnosis of GM2 activator deficiency is established in a proband with suggestive findings, normal beta-hexosaminidase A (HEX A) enzyme activity levels, and biallelic …

WebTwo patients from Turkey with a novel variant in the GM2A gene and review of the literature. GM2-GM3 gangliosides ratio is dependent on GRP94 through down-regulation of GM2-AP cofactor in brain metastasis cells. Review of GM2A mutations causing GM2 activator protein deficiency and GM2 gangliosidosis-AB variant.

WebSep 11, 2007 · Weight Average: 257.223 Monoisotopic: 257.102824366 Chemical Formula C 8 H 20 NO 6 P Synonyms (2R)-2,3-dihydroxypropyl 2-(trimethylammonio)ethyl … oregon bench probation rulesWebUse a concentration of 0.04 - 0.4 µg/ml. Predicted molecular weight: 21 kDa. Target. Function. Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates … how to unblock a vacuum cleaner hoseWebGM2-gangliosidosis, AB variant is a rare inherited disorder that progressively destroys nerve cells (neurons) in the brain and spinal cord. Signs and symptoms of the AB variant … how to unblock a web addressWebPredicted molecular weight. 19 kDa including tags. Amino acids. 26 to 193. Tags. His tag C-Terminus. Additional sequence information. This product is the full length protein from aa 26 to 193. The signal peptide is not included (NP_000396.2). ... Defects in GM2A are the cause of GM2-gangliosidosis type AB (GM2GAB) [MIM:272750]; also known as ... oregon behavioral health integrationWebExaminations at school age showed height and weight below the third centiles with head circumference at the 50th centile. Neurological examination disclosed mild spastic quadriparesis, limb ... GM2A encodes for the GM2 activator protein required for the extraction of lipids from bilayers, lipid solubilization, and presentation ... oregon bench chain grinder partsWebJul 9, 2015 · Height and weight were , 3% but. head circumference was normal. A cherry red spot was conspicuously. ... GM2A is an established gene for GM2-gangliosidosis, AB variant (MIM: 272750). how to unblock axis bank debit card onlineWebWestern Blot: GM2A Overexpression Lysate (Adult Normal) [NBL1-11135] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GM2A. ... Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post ... how to unblock axis bank debit card by sms