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Btg2 cancer

WebApr 11, 2024 · VprBP (also known as DCAF1) is a recently identified kinase that is overexpressed in cancer cells and serves as a major determinant for epigenetic gene silencing and tumorigenesis. The role of ... WebBTG2 is a tumor suppressor gene. It is frequently downregulated in human cancer tissues, and its loss is associated with cancer cell metastasis, suggesting that the suppression of …

BTG2 increases breast cancer cell DNA damage after irradiation.

WebTherefore, BTG2 is considered to be a novel tumor suppressor gene for many types of cancer, such as laryngeal cancer [10] gastric cancer [11], liver cancer and breast cancer [12]. WebBTG2. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. … seven deadly sins oc powers https://amythill.com

BTG2 gene predicts poor outcome in PT-DLBCL JIR

WebThe p53-inducible anti-proliferative gene, BTG2, is suppressed in many cancers and its loss is associated with tumor progression. 1 The absence of inactivating gene mutations in BTG2 suggests that epigenetic regulation might be a predominant mechanism of its silencing. Histone lysine methyl transferases are a class of histone modifying enzymes, which … WebPTEN activity inhibitor (VO-OHpic) treatment decreased BTG2 expression in RT-4 and PTEN-overexpressed T24 cells. Our results suggested that BTG2 functioned as a bladder cancer tumor suppressor gene, and was induced by p53 and PTEN. Modulation of BTG2 expression seems a promising way to treat human bladder cancer. WebJun 22, 2024 · 4 Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, Jiangsu, ... Knockdown of KIAA1429 significantly decreased the m6A levels of BTG2 mRNA, leading to enhanced YTH m6A RNA binding protein 2 (YTHDF2, … seven deadly sins occasion

BTG2 - Wikipedia

Category:BTG2 BTG anti-proliferation factor 2 [ Homo sapiens (human) ]

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Btg2 cancer

BTG2 BTG anti-proliferation factor 2 [ (human)] - National …

WebAlthough widely deemed as a tumor suppressor gene, the role of B-cell translocation gene 2 (BTG2) in bladder cancer is still inconclusive. We investigated the role and regulatory … WebApr 10, 2024 · Genetic classification helps to disclose molecular heterogeneity and therapeutic implications in diffuse large B-cell lymphoma (DLBCL). Using whole exome/genome sequencing, RNA-sequencing, and ...

Btg2 cancer

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WebBTG2. Protein BTG2 also known as BTG family member 2 or NGF-inducible anti-proliferative protein PC3 or NGF-inducible protein TIS21, is a protein that in humans is encoded by the BTG2 gene ( B -cell t ranslocation g ene 2) [5] and in other mammals by the homologous Btg2 gene. [6] [7] This protein controls cell cycle progression and proneural ...

WebMar 21, 2024 · Elevated BTG2 improves the radiosensitivity of non-small cell lung cancer (NSCLC) through apoptosis. Zhu C, et al.Thorac Cancer, 2024 May. PMID 35388633, Free PMC Article MicroRNA miR-92a-3p regulates breast cancer cell proliferation and metastasis via regulating B-cell translocation gene 2 (BTG2). WebOct 23, 2024 · In prostate cancer, BTG2 is a target of miR-32, miR-21, and its suppression results in disease initiation and progression, therapy resistance, and metastasis (Coppola et al., 2013; Jalava et al., 2012). These findings point to a predominantly tumor suppressive function for BTG2.

WebThe BTG2 expression is downregulated in many human cancers. It is an instantaneous early response gene and plays important roles in cell … WebJun 16, 2010 · BTG2 is known to mediate chemotherapy induced apoptosis in cancer cells [29–31] and a study by Lim et al. indicates that BTG2 enhances cancer cell death by accumulation of H 2 O 2 . Down-regulation of BTG2 has been observed in several cancer types such as prostate cancer, breast cancer and gliomas [17, 18, 33]. In this study …

WebB-cell translocation gene 2 (BTG2) is a tumour suppressor protein known to be downregulated in several types of cancer. In this study, we investigated a potential role …

WebApr 4, 2013 · We investigated whether downregulation of the basal protein B-cell translocation gene 2 (BTG2) is implicated in prostate cancer transformation and progression. Here we show that BTG2 loss can shift normal prostate basal cells towards luminal markers expression, a phenotype also accompanied by the appearance of … seven deadly sins not animeWebRelationship Between BTG2 Expression and Clinicopathological Factors in LUAD. Next, we evaluated the correlations between BTG2 expression and the clinicopathological factors (cancer stages, status of lymph node metastasis (LNM), age, gender, smoking habits, race). Results from the UALCAN database showed that the BTG2 expression was significantly … thetovlifeWebBTG2 expression was elevated upon IR exposure, in a dose-dependent but not a time-dependent manner. CCK-8 and EDU assays revealed that BTG2 overexpression … seven deadly sins online czWebThe purposes of this study were to investigate the effects of B cell translocation gene 2 (BTG2) on the proliferation, apoptosis, and invasion of triple-negative breast cancer and … seven deadly sins of social mediaWebOct 1, 2024 · According to a research by Mourits et al., TLR10 does affect the induction of BCG-induced trained immunity in vitro. However, its role in vivo is still an open debate, as genetic variation in TLR10 gene does not affect the induction of trained immunity by BCG vaccination (Mourits et al. 2024 ). the tovar hotelWebSep 23, 2024 · BTG2 and YY1 may be crucial therapeutic targets to intervene in metabolic dysfunction in response to the GH-dependent signaling pathway. ... J. A. et al. Inhibition of breast cancer invasion by ... the toussaint knight\\u0027s steel swordWebJun 16, 2010 · BTG2 is known to mediate chemotherapy induced apoptosis in cancer cells [29–31] and a study by Lim et al. indicates that BTG2 enhances cancer cell death by … seven deadly sins of business selling